8-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene → HCID 67057737, 화합물

HRID 604667노트

반응식

HRID 604667 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH:10]=2)=[CH:5][CH:4]=1>CCO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1

참가 물질

4

반응물 1

HCID 148634918-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene

생성물 1

HCID 67057737HCID 67057737, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene (526.8 mg, 2.14 mmoL) in EtOH (20 mL) was added 10% Pd/C (50 mg). The reaction was put under an atmosphere of H2 (balloon) and stirred vigorously at room temperature. After 1.5 hours, the catalyst was removed by filtration. The filtrate was concentrated to afford 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane. 1H NMR (500 MHz, CDCl3): δ 7.14-7.17 (m, 2H), 6.82-6.85 (m, 2H), 3.98 (s, 4H), 3.79 (s, 3H), 2.52 (m, 1H), 1.64-1.86 (m, 8H).

후처리

  1. customthe catalyst was removed by filtration
  2. concentrationThe filtrate was concentrated

출처 및 근거

ORD 기록
ord-f9e80bc20e31475ab37f48e1c6ff31e8
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07910592B2

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