Water → HCID 67040477, 화합물

HRID 605311노트

반응식

HRID 605311 반응식
[CH2:1]([O:3][C:4]([C:6]1[S:7][C:8](Cl)=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)=[O:5])[CH3:2].[SH:15][C:16]1[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=1.C(=O)([O-])[O-].[Cs+].[Cs+].O>CN(C)C=O>[CH2:1]([O:3][C:4]([C:6]1[S:7][C:8]([S:15][C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)=[O:5])[CH3:2]

참가 물질

6

반응물 4

HCID 962WaterHCID 10796Cesium carbonateHCID 2401474-MercaptophenolHCID 56763846HCID 56763846, 화합물

생성물 1

HCID 67040477HCID 67040477, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

The product from Example 351A (1 equiv) and 4-mercaptophenol (1 equiv) were dissolved in dimethylformamide and cesium carbonate (5 equiv) added. The resultant mixture was stirred at 80° C. for 2.5 hours, cooled to room temperature and water added. The solution was extracted with ethyl acetate, the organic extracts dried and concentrated under vacuum to provide the title product.

후처리

  1. extractionThe solution was extracted with ethyl acetate
  2. customthe organic extracts dried
  3. concentrationconcentrated under vacuum

출처 및 근거

ORD 기록
ord-149745779bac4c5f9a7501b9b1308c5e
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07910595B2

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