Ethyl Acetate → 4-(4-tert-Butoxycarbonylamino-phenylsulfanyl)-3-(7-tert-butyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

반응식

[C:1]([C:5]1[N:10]=[C:9]([N:11]=[CH:12][N:13](C)C)[C:8]([C:16]#[N:17])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:18][O:19][C:20](=[O:43])[C:21]1[CH:26]=[CH:25][C:24]([S:27][C:28]2[CH:33]=[CH:32][C:31]([NH:34][C:35]([O:37][C:38]([CH3:41])([CH3:40])[CH3:39])=[O:36])=[CH:30][CH:29]=2)=[C:23](N)[CH:22]=1.CCOC(C)=O.C([O-])([O-])=O.[K+].[K+]>CC(O)=O.O>[CH3:18][O:19][C:20](=[O:43])[C:21]1[CH:22]=[CH:23][C:24]([S:27][C:28]2[CH:33]=[CH:32][C:31]([NH:34][C:35]([O:37][C:38]([CH3:40])([CH3:39])[CH3:41])=[O:36])=[CH:30][CH:29]=2)=[C:25]([NH:17][C:16]2[C:8]3[CH:7]=[CH:6][C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[N:10][C:9]=3[N:11]=[CH:12][N:13]=2)[CH:26]=1