Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 606240생성일: 2026년 10월 25일
4-(Phenoxymethyl)piperidine → 2-Tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine
https://huagongshe.com/reaction/606240
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-(Phenoxymethyl)piperidine | HCID 3017444 | — |
| 반응물 | 2-Tert-butoxy-6-vinylpyrazine | HCID 22248276 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine | HCID 22248528 | — |
반응 단계
After dissolving 471 mg of 2-tert-butoxy-6-vinylpyrazine and 505 mg of 4-(phenoxymethyl)piperidine in 10 ml of ethanol, the mixture was stirred for 4 days at 80° C. The reaction solution was concentrated under reduced pressure and the residue was purified by NH silica gel column chromatography (solvent: n-hexane/ethyl acetate) to obtain 2-tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07915274B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_03 |
|---|
| ORD ID | ord-9e16f06448fc4f8fb6369ece4d7ea4d2 |
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| 출처 메모 | uspto-grants-2011_03 |
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