Sulfuric Acid → 2-Amino-5-nitrobenzamide

HRID 606489

반응식

HRID 606489 반응식
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].S(=O)(=O)(O)[OH:14]>>[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]([NH2:5])=[O:14]

참가 물질

3

반응물 2

HCID 1118Sulfuric AcidHCID 285322-Amino-5-nitrobenzonitrile

생성물 1

HCID 976652-Amino-5-nitrobenzamide

반응 조건

온도
130 °C

실험 절차

A mixture of 2-amino-5-nitrobenzonitrile (25.4 g) and sulfuric acid (70 mL) was stirred at 130° C. for 40 min. The reaction mixture was added slowly to ice water, and the precipitate was collected by filtration, washed with water, ethanol and diethyl ether to give 2-amino-5-nitrobenzamide (24.6 g).

후처리

  1. filtrationthe precipitate was collected by filtration
  2. washwashed with water, ethanol and diethyl ether

출처 및 근거

ORD 기록
ord-81a291086d23419792bc4437853ea22c
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915267B2

연결된 노트

불러오는 중…