1,2-Dimethylimidazole → HCID 86617157, 화합물

HRID 606556

반응식

HRID 606556 반응식
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[CH3:18][N:19]1[CH:23]=[CH:22][N:21]=[C:20]1[CH3:24]>CC#N>[Cl-:1].[CH3:18][N+:19]1[CH:23]=[CH:22][N:21]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:20]=1[CH3:24]

참가 물질

4

반응물 2

HCID 156171,2-DimethylimidazoleHCID 209931-Chlorohexadecane

생성물 1

HCID 86617157HCID 86617157, 화합물수율 62%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

반응 조건

온도
80 °C

실험 절차

To a 2 L three-necked round bottom flask equipped with overhead mechanical stirrer were added 1-chlorohexadecane (260 g, 1.00 moles), 1,2 dimethylimidazole (91.0 g, 0.95 moles), and CH3CN (500 mL) and the two-phase reaction mixture was vigorously stirred in an oil bath at 80° C. After 72 h, the reaction mixture was cooled to room temperature and the product was crystallized overnight. The crystallized solid was filtered, thoroughly washed with cold CH3CN, and vacuum dried at 70° C. for 3 days to give 1,2-dimethyl-3-hexadecylimidazolium chloride as a slightly off-white solid, 220 g, 62% yield.

후처리

  1. customTo a 2 L three-necked round bottom flask equipped with overhead mechanical stirrer
  2. customthe two-phase reaction mixture
  3. temperaturethe reaction mixture was cooled to room temperature
  4. customthe product was crystallized overnight
  5. filtrationThe crystallized solid was filtered
  6. washthoroughly washed with cold CH3CN, and vacuum
  7. customdried at 70° C. for 3 days

출처 및 근거

ORD 기록
ord-a24e5dd4147d4b6e9c248ec7e7069ac6
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915332B2

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