1-Methylimidazole → HCID 67047038, 화합물

HRID 607498노트

반응식

HRID 607498 반응식
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[CH3:11])=[CH:6][CH:5]=1)=[CH2:3].CN1C=CN=C1.[N+](=[CH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[N-]>C1(C)C=CC=CC=1>[C:10]([C:7]1[CH:8]=[CH:9][C:4]([C:2]2([CH3:3])[CH2:1][CH:21]2[C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:5][CH:6]=1)(=[O:12])[CH3:11]

참가 물질

5

반응물 3

HCID 13901-MethylimidazoleHCID 12192Ethyl diazoacetateHCID 589438p-Isopropenylacetophenone

생성물 1

HCID 67047038HCID 67047038, 화합물수율 22%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a stirred solution of 1-[4-(1-methylethenyl)phenyl]ethanone (711 mg, 4.44 mmol, trans) (Org. Lett., 2002, 4(1), 107-109), N-methylimidazole (1.06 ml, 13.3 mmol) and Co(TPP) (89 mg, 0.13 mmol) in toluene (10 ml) was added ethyl diazoacetate (0.65 ml, 6.21 mmol) in one portion at ambient temperature. The same procedure as described in Example 2H was performed to give the title compound (236 mg, 22%) as dark yellow oil.

출처 및 근거

ORD 기록
ord-ed58b3e899f345e988a501950cd767f0
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915448B2

반응 노트

불러오는 중…