Trifluoroacetic acid → N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

HRID 607614노트

반응식

HRID 607614 반응식
[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH:5]C(=O)OC(C)(C)C.[C:19]([OH:25])([C:21]([F:24])([F:23])[F:22])=[O:20]>C(Cl)Cl>[F:22][C:21]([F:24])([F:23])[C:19]([OH:25])=[O:20].[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH2:5]

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 59216311Tert-butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate

생성물 1

HCID 66813129N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

tert-Butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate was stirred with DCM (0.5 ml) and TFA (0.5 ml) for 30 min. The volatiles were removed under reduced pressure to yield the product.

후처리

  1. customThe volatiles were removed under reduced pressure
  2. customto yield the product

출처 및 근거

ORD 기록
ord-1c33a2ca1ca6438bb46e2785f4c5d3ff
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915408B2

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