o-Phenylbenzoic acid → Methyl 1-(biphenylcarbonyl)-5-oxopiperidine-2-carboxylate

반응식

[O:1]=[C:2]1[CH2:7][NH:6][CH:5]([C:8]([O:10][CH3:11])=[O:9])[CH2:4][CH2:3]1.[C:12]1([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:13]([C:18](O)=[O:19])=[CH:14][CH:15]=[CH:16][CH:17]=1>>[C:12]1([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:13]([C:18]([N:6]2[CH2:7][C:2](=[O:1])[CH2:3][CH2:4][CH:5]2[C:8]([O:10][CH3:11])=[O:9])=[O:19])=[CH:14][CH:15]=[CH:16][CH:17]=1

참가 물질

반응물 2

HCID 70357o-Phenylbenzoic acid

HCID 83854465Methyl 5-oxopiperidine-2-carboxylate

생성물 1

HCID 89739424Methyl 1-(biphenylcarbonyl)-5-oxopiperidine-2-carboxylate

실험 절차

Methyl 1-(biphenylcarbonyl)-5-oxopiperidine-2-carboxylate was prepared according to general procedure A using methyl 5-oxopiperidine-2-carboxylate and biphenyl-2-carboxylic acid. MS (ESI) 338 (M+H).

출처 및 근거

ORD 기록: ord-6b0a6d272753454b8c1044669df45877
출처 데이터셋: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09440982B2

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