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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 60858생성일: 2026년 10월 26일

2,5-Dichloropyrimidine → rac-cis-(2-(((5-Chloropyrimidin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

https://huagongshe.com/reaction/60858

반응식

참여 물질

역할이름HCID투입량
반응물2,5-DichloropyrimidineHCID 590641—
반응물rac-cis-(2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanoneHCID 131737144—
생성물rac-cis-(2-(((5-Chloropyrimidin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanoneHCID 131737145—

반응 단계

The title compound was prepared following the same general protocol as described for Example 16 starting with rac-cis-(2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 2,5-dichloropyrimidine. MS (ESI) 426.4 (M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09440982B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-6bc34c47989c45d2ab602de454c83763
출처 메모uspto-grants-2016_09