2-Chloro-4-methoxypyrimidine → 2-(4-Methoxy-2-pyrimidinyl)-5-methylbenzoic acid

HRID 60925

반응식

HRID 60925 반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2C=N[CH:14]=[CH:13][N:12]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].ClC1[N:23]=[C:22]([O:24][CH3:25])C=CN=1>>[CH3:25][O:24][C:22]1[CH:14]=[CH:13][N:12]=[C:11]([C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=2[C:7]([OH:9])=[O:8])[N:23]=1

참가 물질

3

반응물 2

HCID 5889352-Chloro-4-methoxypyrimidineHCID 811116085-Methyl-2-(2-pyrazinyl)benzoic acid

생성물 1

HCID 1177278632-(4-Methoxy-2-pyrimidinyl)-5-methylbenzoic acid

실험 절차

The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting from 2-chloro-4-methoxypyrimidine. ESI-MS (m/z): 245 [M+1]+.

출처 및 근거

ORD 기록
ord-5a715927cf5b4426a72171e2e0f791ae
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09440982B2

연결된 노트

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