N-Piperidinoethanol → SB 203186

반응식

[N:1]1([CH2:7][CH2:8][OH:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([C:19](Cl)=[O:20])=[CH:11]1>>[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([C:19]([O:9][CH2:8][CH2:7][N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[O:20])=[CH:11]1

참가 물질

반응물 2

HCID 18232N-Piperidinoethanol

HCID 123802781H-Indole-3-carbonyl chloride

생성물 1

HCID 3272300SB 203186

실험 절차

1-Piperidineethanol was reacted with 1H-indole-3-carboxylic acid chloride using the method described in Example 1 a to afford 2-(1-piperidyl)ethyl 1H-indole-3-carboxylate.

출처 및 근거

ORD 기록: ord-2443697cff5a44b3ad3dec91489c357e
출처 데이터셋: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05998409

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