Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodoethane → N-[(1-Ethyl-4-piperidyl)methyl] 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | N-(4-Piperidylmethyl) 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide | HCID 9839803 | — |
| 생성물 | N-[(1-Ethyl-4-piperidyl)methyl] 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide | HCID 19599438 | — |
반응 단계
N-(4-Piperidylmethyl) 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide (E21) was alkylated with iodoethane using the method of Example 22. The title compound was obtained as a white solid (27%), which was converted to its hydrochloride salt and crystallised from acetone/ethanol/ether as a white solid mp 243-245° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05998409 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-0e2a880d9c8e423a96e119465c41fe08 |
| 출처 메모 | uspto-grants-1999_12 |