N-(2-Aminoethyl)piperidine → N-[2-(1-Piperidyl)ethyl] 1H-indole-3-carboxamide

반응식

[N:1]1([CH2:7][CH2:8][NH2:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([C:19](Cl)=[O:20])=[CH:11]1>>[N:1]1([CH2:7][CH2:8][NH:9][C:19]([C:12]2[C:13]3[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=3)[NH:10][CH:11]=2)=[O:20])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 33944N-(2-Aminoethyl)piperidine

HCID 123802781H-Indole-3-carbonyl chloride

생성물 1

HCID 10635843N-[2-(1-Piperidyl)ethyl] 1H-indole-3-carboxamide

실험 절차

1-Piperidineethylamine was reacted with 1H-indole-3-carboxylic acid chloride using the method described in Description 1 to afford the title compound (D2) as a beige solid.

출처 및 근거

ORD 기록: ord-1a878120141342c99d35bd80246da004
출처 데이터셋: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05998409

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