(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole → 5-bromo-3-[2-(N,N-dimethylamino)ethyl]-1-benzoylindole

HRID 609728

반응식

HRID 609728 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[CH2:19][C@H:20]1CC[CH2:22][N:21]1[CH3:25].BrC1C=C2C(=CC=1)NC=C2C[C@H]1CCCN1C>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[CH2:19][CH2:20][N:21]([CH3:22])[CH3:25]

참가 물질

3

반응물 2

HCID 11185464(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indoleHCID 54038939(R)-5-Bromo-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

생성물 1

HCID 196004435-bromo-3-[2-(N,N-dimethylamino)ethyl]-1-benzoylindole

실험 절차

(R)-5-Bromo-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole: (76%), from (R)-5-Bromo-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole (Example 3d).

출처 및 근거

ORD 기록
ord-67b62456c2b34548a4107df3a06c8518
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998438

연결된 노트

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