참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzoyl chloride, 3-nitro- | HCID 8495 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Nitrobenzanilide | HCID 347755 | — |
반응 단계
To a cooled (0° C.) solution of aniline (17 g, 180 mmol) and triethylamine (27 mL, 190 mmol) in dichloromethane (100 mL) was added a solution of 3-nitrobenzoyl chloride (30 g, 160 mmol) in dichloromethane (60 mL). The mixture was stirred for 15 min at 0° C. then overnight at room temperature. It was then poured into saturated sodium bicarbonate (1 L) and stirred vigorously for 15 min. The precipitate was collected, washed with water and dried (40 g, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05998463 |
|---|
| 출처 데이터셋 | uspto-grants-1999_12 |
|---|
| ORD ID | ord-68e152fdc1f3477bba21a2bec2bf8b0b |
|---|
| 출처 메모 | uspto-grants-1999_12 |
|---|
