Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Chloromethyl)quinoline → (+/-)-cis-3-(3-Pyridyloxy)-6-(2-quinolyl)methoxy-4-chromanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Chloromethyl)quinoline | HCID 20394 | — |
| 반응물 | 2-(Chloromethyl)-6-fluoroquinoline | HCID 11241007 | — |
| 반응물 | HCID 67592373 | HCID 67592373 | — |
| 생성물 | (+/-)-cis-3-(3-Pyridyloxy)-6-(2-quinolyl)methoxy-4-chromanol | HCID 67612913 | — |
반응 단계
By the methods of the preceding Example, substituting a molar equivalent of 2-chloromethylquinoline for the 6-fluoro-2-chloromethylquinoline, the title product of Example 74 (0.26 g) was converted to present chromatoqraphed title product, 0.35 g (88%), also recrystallized from isopropyl ether/CH2Cl2, m.p. 126-128° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05998451 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-98827f33d9a54363a168f60ac11001b0 |
| 출처 메모 | uspto-grants-1999_12 |