Cyclopropanecarbonyl chloride → 5-(N-[cyclopropanecarbonyl]amino)-3-(ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

HRID 610559

반응식

HRID 610559 반응식
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[CH:19]1([C:22](Cl)=[O:23])[CH2:21][CH2:20]1>>[CH:19]1([C:22]([NH:1][C:2]2[N:7]=[C:6]3[C:8]([CH:11]4[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]4)=[CH:9][NH:10][C:5]3=[CH:4][CH:3]=2)=[O:23])[CH2:21][CH2:20]1

참가 물질

3

반응물 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 117706865-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

생성물 1

HCID 196015285-(N-[cyclopropanecarbonyl]amino)-3-(ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

실험 절차

Beginning with 0.015 gm (0.061 mMol) 5-amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.008 mL (0.080 mMol) cyclopropanecarbonyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

출처 및 근거

ORD 기록
ord-7c937f6758e04f1b9f1203efd4afaac0
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998622

연결된 노트

불러오는 중…