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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 61082생성일: 2026년 10월 25일

2-Bromo-5-chloropyridine → ((2S,3R)-2-(((5-Chloropyridin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(2-(5-fluoropyridin-2-yl)-5-methylphenyl)methanone

https://huagongshe.com/reaction/61082

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-5-chloropyridineHCID 817098—
반응물((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-(5-fluoropyridin-2-yl)-5-methylphenyl)methanoneHCID 117727820—
생성물((2S,3R)-2-(((5-Chloropyridin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(2-(5-fluoropyridin-2-yl)-5-methylphenyl)methanoneHCID 117727898—

반응 단계

The title compound was prepared following the same general protocol as described for Example A44 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(2-(5-fluoropyridin-2-yl)-5-methylphenyl)methanone and 2-bromo-5-chloropyridine. MS (ESI) 453 (M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09440982B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-f45a882333e94baf8c54c2b741c7f1c0
출처 메모uspto-grants-2016_09