돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 61108생성일: 2026년 10월 26일

2-Chloro-5-fluoropyrimidine → ((2S,3R)-2-(((5-Fluoropyrimidin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridin-2-yl)phenyl)methanone

https://huagongshe.com/reaction/61108

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-5-fluoropyrimidineHCID 583466—
반응물((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridin-2-yl)phenyl)methanoneHCID 117727920—
생성물((2S,3R)-2-(((5-Fluoropyrimidin-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridin-2-yl)phenyl)methanoneHCID 117728393—

반응 단계

The title compound was prepared following the same general protocol as described for Example A1, using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridin-2-yl)phenyl)methanone and 2-chloro-5-fluoropyrimidine. ESI-MS (m/z): 420 [M+1]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09440982B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-72a798eba2a847968aa17791b3665574
출처 메모uspto-grants-2016_09