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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 61120생성일: 2026년 10월 26일

2-Chloro-5-pyrimidinecarbonitrile → 2-((((2S,3R)-3-Methyl-1-(6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinoyl)piperidin-2-yl)methyl)amino)pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/61120

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-5-pyrimidinecarbonitrileHCID 21473592—
반응물((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)methanoneHCID 117727634—
생성물2-((((2S,3R)-3-Methyl-1-(6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinoyl)piperidin-2-yl)methyl)amino)pyrimidine-5-carbonitrileHCID 117727644—

반응 단계

The title compound was prepared following the same general protocol as described for Example A1, using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)methanone and 2-chloropyrimidine-5-carbonitrile. ESI-MS (m/z): 418 [M+1]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09440982B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-882644f664764ac591845b4192c061fa
출처 메모uspto-grants-2016_09