HCID 19600120, 화합물 → Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

HRID 611242노트

반응식

HRID 611242 반응식
C([N:8]1[CH2:13][CH2:12][C:11]2[CH:14]=[C:15]([C:17]([O:19][CH3:20])=[O:18])[O:16][C:10]=2[CH2:9]1)C1C=CC=CC=1>CO.[C].[Pd]>[O:16]1[C:10]2[CH2:9][NH:8][CH2:13][CH2:12][C:11]=2[CH:14]=[C:15]1[C:17]([O:19][CH3:20])=[O:18]

참가 물질

4

반응물 1

HCID 19600120HCID 19600120, 화합물

생성물 1

HCID 19600098Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 887Methanol용매

실험 절차

A solution of 0.285 g (1.050 mmol) of methyl 6-benzyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate in 30 ml of methanol was hydrogenated at room temperature at atmospheric pressure over 0.2 g of 10% palladium-carbon (50% wet) overnight. After the catalyst was filtered off, the filtrate was evaporated under reduced pressure to yield the desired product.

후처리

  1. filtrationAfter the catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-bef794c704fe44a4bed37bbfb8a46dbd
출처 데이터셋
uspto-grants-1999_12
특허 번호
US05998433

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