Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methoxyaniline → 4-Bromo-2-methoxyaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methoxyaniline | HCID 7000 | — |
| 반응물 | 2,4,4,6-Tetrabromocyclohexa-2,5-dienone | HCID 88433 | — |
| 생성물 | 4-Bromo-2-methoxyaniline | HCID 459257 | — |
반응 단계
2-Methoxyaniline was brominated with 2,4,4,6-tetrabromo-2,5-cyclohexadien-1-one to give 4-bromo-2-methoxyaniline which was reacted with di-tert-butyldicarbonate in tetrahydrofuran to protect the amine group. The product was treated with butyllithium at -78° C. and then with trimethyltin chloride to give 4-tert-butoxycarbonylamino-3-methoxyphenyl trimethyl stannane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06001839 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-81be778add174383838e4f6b692fb180 |
| 출처 메모 | uspto-grants-1999_12 |