Methanol → tert-butyl (2R)-2-ethynylpyrrolidine-1-carboxylate

HRID 611556

반응식

[C:1]([N:8]1[CH2:15][CH2:14][CH2:13][C@@H:9]1[C:10](O)=O)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[CH3:16]O>>[C:1]([N:8]1[CH2:15][CH2:14][CH2:13][C@@H:9]1[C:10]#[CH:16])([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2]

참가 물질

반응물 2

HCID 887Methanol

HCID 688022(2R)-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid

생성물 1

HCID 10262067tert-butyl (2R)-2-ethynylpyrrolidine-1-carboxylate

실험 절차

The title compound was prepared from N-BOC-(R)-proline according to the procedures of Examples 1a-c above. [α]D≤ +113.0 (c 0.94, MeOH).

출처 및 근거

ORD 기록: ord-b3f1ac7e02084590be711e7f3752adb6
출처 데이터셋: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06001849

연결된 노트

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