Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-Methoxy-6-methylbenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Methoxy-6-methyl-benzoic acid ethyl ester | HCID 591060 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Methoxy-6-methylbenzoic acid | HCID 273170 | — |
반응 단계
A mixture of ethyl 6-methyl-2-methoxybenzoate (642.0 g, 3.3 mol), water (2.5 l), ethanol (4.0 l) and sodium hydroxide (270 g, 6.6 mol) is heated under reflux with stirring for 20 hours. Subsequently, ethanol is distilled off and the reaction mixture is diluted with water, acidified with concentrated hydrochloric acid. The solid material is collected by vacuum filtration, washed with water and dried yielding off-white crystals, 460.0 g (83.9%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06001883 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-52785138e4334a1d99244b55c52f6e0d |
| 출처 메모 | uspto-grants-1999_12 |