Bromobenzene → Triphenylborane

HRID 611958

반응식

HRID 611958 반응식
C[B-:2]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C[N+](C)(C)C.C1(Br)C=CC=CC=1.[Mg].B(F)(F)F.CCOCC>C(OCC)C>[C:15]1([B:2]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

참가 물질

6

반응물 4

HCID 7961BromobenzeneHCID 8000Boron trifluoride etherateHCID 5462224MagnesiumHCID 13498337Tetramethylammonium methyltriphenylborate

생성물 1

HCID 70400Triphenylborane

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

More specifically, in the case of the tetramethylammonium methyltriphenylborate, phenyl bromide is reacted with metallic magnesium in diethyl ether to prepare a Grignard reagent, the reagent is added dropwise to a solution containing boron trifluoride diethyl etherate dissolved in diethyl ether, the mixed solution is stirred for several hours to obtain triphenylborane, the triphenylborane obtained is added to methyllithium without passing through isolation to form lithium methyltriphenylborate, and tetramethylammonium bromide is added thereto to effect ion exchanging, as a result, tetramethylammonium methyltriphenylborate is obtained.

후처리

  1. additionthe reagent is added dropwise to a solution

출처 및 근거

ORD 기록
ord-d43520512c3c4def86ee4482ed62ddf2
출처 데이터셋
uspto-grants-1999_12
특허 번호
US06002044

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