Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 612116생성일: 2026년 10월 26일
Dimethylformamide dimethyl acetal → Methyl 4-ethoxy-5-methoxy-2-(dimethylaminomethyleneamino)benzoate
https://huagongshe.com/reaction/612116
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | Methyl 2-amino-4-ethoxy-5-methoxybenzoate | HCID 10489373 | — |
| 용매 | N,N-dimethylformamide N,N-dimethylacetamide | HCID 22628260 | — |
| 생성물 | Methyl 4-ethoxy-5-methoxy-2-(dimethylaminomethyleneamino)benzoate | HCID 10779127 | 97.1% |
반응 단계
A mixture of 15.056 g (66.9 mmol) methyl 2-amino-4-ethoxy-5-methoxybenzoate and 14.1 ml (100 mmol) N,N-dimethylformamide dimethylacetal was heated to 100° C. under N2. At 4.5 hours added 4.7 ml (33.3 mmol) more DMF/DMA and removed heat at 5 hours. Stripped solvent, azeotroped with toluene, and dried in vacuo, giving 18.211 g of grey-brown solid: mass spectrum (electrospray m/e): M+H=281.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06002008 |
|---|
| 출처 데이터셋 | uspto-grants-1999_12 |
|---|
| ORD ID | ord-b625d53183804ba2bb7b702fdf150b11 |
|---|
| 출처 메모 | uspto-grants-1999_12 |
|---|
