Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydrazinylpyridine hydrochloride → N-[2-(3-Methoxy-4-benzyloxyphenyl)-ethylidene]-N'-pyridin-4-yl-hydrazine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydrazinylpyridine hydrochloride | HCID 22320258 | — |
| 반응물 | 1-Benzyloxy-2-methoxy-4-(2-methoxyvinyl)benzene | HCID 54126247 | — |
| 촉매 | p-Toluenesulfonic acid | HCID 6101 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[2-(3-Methoxy-4-benzyloxyphenyl)-ethylidene]-N'-pyridin-4-yl-hydrazine hydrochloride | HCID 70107929 | 61% |
반응 단계
To a stirred solution of 1-benzyloxy-2-methoxy-4-(2-methoxyvinyl)benzene (11.0 g), 4-hydrazinopyridine hydrochloride (6.6 g), and ethanol (150 ml) was added p-toluene sulfonic acid (0.39 g). The reaction mixture was stirred under reflux for 2 hrs and concentrated in vacuo. Recrystallization of the residue from methanol/ether gave 9.48 g (61%) of product, mp 154-155° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06004977 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-b384a5500f894d13a7df96d4374ea1cd |
| 출처 메모 | uspto-grants-1999_12 |