HCID 19596499, 화합물 → 3-(2-Dimethylaminoethoxy)-5-phenylisoxazole hydrochloride
반응식
[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][O:5][C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[O:8][N:7]=1.[ClH:18].O1CCOCC1>O1CCOCC1>[ClH:18].[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][O:5][C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[O:8][N:7]=1참가 물질
4
실험 절차
3-(2-Dimethylaminoethoxy)-5-phenylisoxazole (130 mg) was dissolved in dioxane (1.0 ml), and a solution of 4N hydrochloric acid/dioxane (0.2 ml) was added thereto, and the resulting mixture was allowed to stand at room temperature for 15 minutes. The solvent was evaporated under reduced pressure and the residue was washed with ethyl acetate (5 ml) to obtain the title compound (148 mg, 98%) as colorless crystals.
후처리
- customThe solvent was evaporated under reduced pressure
- washthe residue was washed with ethyl acetate (5 ml)
출처 및 근거
- ORD 기록
- ord-5017179cea2943169bd51fcbc8fb9bad
- 출처 데이터셋
- uspto-grants-1999_12
- 특허 번호
- US06005116
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