Phosgene → HCID 12445506, 화합물

HRID 614335노트

반응식

HRID 614335 반응식
Cl.[NH2:2][C:3]1[C:4]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[F:16])=[N:5][CH:6]=[CH:7][CH:8]=1.[C:17](Cl)(Cl)=[O:18]>O>[F:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[N:9]1[C:4]2=[N:5][CH:6]=[CH:7][CH:8]=[C:3]2[NH:2][C:17]1=[O:18]

참가 물질

4

반응물 2

HCID 6371PhosgeneHCID 21329317HCID 21329317, 화합물

생성물 1

HCID 12445506HCID 12445506, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The product from step B (1.5 g.) was dissolved in 40 ml. of water and treated with phosgene as described in Example 1, Step C, to provide 3-(2-fluorophenyl)-1,3-dihydroimidazo[ 4,5-b] pyridin-2-one, m.p. 199°-200° C.

출처 및 근거

ORD 기록
ord-60fd781d11a24bb1b8580472d4fe9431
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04144341

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