Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitric Acid → 3-Bromo-2-nitro-1-benzofuran
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | 3-Bromo-1-benzofuran | HCID 640589 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Bromo-2-nitro-1-benzofuran | HCID 13509842 | — |
반응 단계
A 5.0 g. sample of powdered 3-bromobenzofuran on a glass dish is placed next to a container of nitric acid. Sodium nitrite is added periodically to the nitric acid, and the entire experiment is covered with a bell jar. After about 15 minutes the powder becomes an oil. After 12 hours the product is dissolved in hot methanol and slowly crystallized by cooling. Recrystallization from methanol provides yellow crystals of 3-bromo-2-nitrobenzofuran, m.p. 130°-132° C. (lit. 132° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04144347 |
| 출처 데이터셋 | uspto-grants-1979_03 |
| ORD ID | ord-e8b879d8638c47dbba8295506a30c2d9 |
| 출처 메모 | uspto-grants-1979_03 |