N-(2-Aminoethyl)piperidine → 2-(2-Oxopyrrolidin-1-yl)-N-[2-(piperidin-1-yl)ethyl]acetamide

HRID 614467

반응식

HRID 614467 반응식
[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH2:7][C:8]([O:10]CC)=O.[N:13]1([CH2:19][CH2:20][NH2:21])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1>>[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH2:7][C:8]([NH:21][CH2:20][CH2:19][N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)=[O:10]

참가 물질

3

반응물 2

HCID 33944N-(2-Aminoethyl)piperidineHCID 109094Ethyl 2-oxopyrrolidine-1-acetate

생성물 1

HCID 443746832-(2-Oxopyrrolidin-1-yl)-N-[2-(piperidin-1-yl)ethyl]acetamide

실험 절차

From 12.8 g. of ethyl 2-oxo-1-pyrrolidineacetate and 19.2 g. of 2-(1-piperidinyl)ethylamine [Compt. rend. 233, 1121 (1951)], following the procedure of Example 1, there is obtained 2-oxo-N-[2-(1-piperidinyl)ethyl]-1-pyrrolidineacetamide; b.p. 185°-187° C./0.15 mm.

출처 및 근거

ORD 기록
ord-f00aab2008df4d2f8fce085f862f8174
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04145347

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