Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester → 2-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester | HCID 574476 | — |
| 반응물 | 2-(Piperidin-1-yl)propan-1-amine | HCID 12455409 | — |
| 생성물 | 2-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide | HCID 21327783 | — |
반응 단계
From 9.3 g. of ethyl 2-methyl-5-oxo-1-pyrrolidineacetate and 10.7 g. of 2-(1-piperidinyl)propylamine (J. Chem. Soc. 1947, 1511), following the procedure of Example 9, there is obtained (±)-2-methyl-5-oxo-N-[2-(1-piperidinyl)propyl]-1-pyrrolidineacetamide; m.p. 111°-112° C. after recrystallization from heptane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04145347 |
| 출처 데이터셋 | uspto-grants-1979_03 |
| ORD ID | ord-c5b7ab7d4a104f209d1703148255e20b |
| 출처 메모 | uspto-grants-1979_03 |