Ethoxalyl chloride → HCID 12909301, 화합물

HRID 614530노트

반응식

HRID 614530 반응식
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][C:8]3=[N:11][C:12]([C:14]([O:16][CH3:17])=[O:15])=[CH:13][N:7]3[C:6]=2[CH:18]=1.[C:19](Cl)(=[O:25])[C:20]([O:22][CH2:23][CH3:24])=[O:21]>CN(C)C=O>[C:19]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][C:8]3=[N:11][C:12]([C:14]([O:16][CH3:17])=[O:15])=[CH:13][N:7]3[C:6]=2[CH:18]=1)([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:25]

참가 물질

4

반응물 2

HCID 20884Ethoxalyl chlorideHCID 12909299HCID 12909299, 화합물

생성물 1

HCID 12909301HCID 12909301, 화합물수율 65%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

By the procedure of Step C in Example 1, methyl 8-amino-4H-imidazo-[2,1-c][1,4]-benzoxazine-2-carboxylate and ethyl chlorooxalate were reacted in dimethylformamide as solvent to obtain a 65% yield of methyl 8-(ethoxalylamino)-4H-imidazo-[2,1-c][1,4]-benzoxazine-2-carboxylate with a melting point of 186°-8° C.

출처 및 근거

ORD 기록
ord-0a2a16f80026419ab071050a51ca05ce
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04145419

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