N-(3-(dimethylamino)propyl)formamide → N,N-dimethyl-N-(5-nitro-1-naphthylmethyl)-N-3-formamidopropylammonium chloride

HRID 614727노트

반응식

HRID 614727 반응식
[CH3:1][N:2]([CH3:9])[CH2:3][CH2:4][CH2:5][NH:6][CH:7]=[O:8].[N+:10]([C:13]1[CH:22]=[CH:21][CH:20]=[C:19]2[C:14]=1[CH:15]=[CH:16][CH:17]=[C:18]2[CH2:23][Cl:24])([O-:12])=[O:11]>O>[Cl-:24].[CH3:1][N+:2]([CH3:9])([CH2:23][C:18]1[C:19]2[C:14](=[C:13]([N+:10]([O-:12])=[O:11])[CH:22]=[CH:21][CH:20]=2)[CH:15]=[CH:16][CH:17]=1)[CH2:3][CH2:4][CH2:5][NH:6][CH:7]=[O:8]

참가 물질

4

반응물 2

HCID 80020N-(3-(dimethylamino)propyl)formamideHCID 2260471-Chloromethyl-5-nitronaphthalene

생성물 1

HCID 86733015N,N-dimethyl-N-(5-nitro-1-naphthylmethyl)-N-3-formamidopropylammonium chloride

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Proceeding in a manner similar to that described above in B-8a, 29.9 parts of N-(3-dimethylaminopropyl)formamide and 44.3 parts of 5-nitro-1-chloromethylnaphthalene were interacted in 30 parts of water to obtain N,N-dimethyl-N-(5-nitro-1-naphthylmethyl)-N-3-formamidopropylammonium chloride. The product was not isolated but was used directly in solution for reduction of the nitro group.

출처 및 근거

ORD 기록
ord-b9a0c7dd909a4d1eb01fdcb8aad31a41
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04146558

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