Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Norfloxacin hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Norfloxacin | HCID 4539 | — |
| 반응물 | 1-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid pentahydrate | HCID 70603524 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Norfloxacin hydrochloride | HCID 12733888 | — |
반응 단계
The compound (I) or (II) was dissolved in ethanol and acidified with concentrated hydrochloric acid. The resulting precipitate was collected, washed with ethanol, and dried to give 1-ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (III) as colorless needles, m.p. above 300° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04146719 |
| 출처 데이터셋 | uspto-grants-1979_03 |
| ORD ID | ord-9db6c02d96a74a82888d23a4fe2324b2 |
| 출처 메모 | uspto-grants-1979_03 |