5-Nitro-2-Furoic Acid → HCID 20429144, 화합물

HRID 615124

반응식

HRID 615124 반응식
[OH-].[CH3:2][Sn+:3]([CH3:5])[CH3:4].[N+:6]([C:9]1[O:13][C:12]([C:14]([OH:16])=[O:15])=[CH:11][CH:10]=1)([O-:8])=[O:7]>C1C=CC=CC=1>[N+:6]([C:9]1[O:13][C:12]([C:14]([O-:16])=[O:15])=[CH:11][CH:10]=1)([O-:8])=[O:7].[CH3:2][Sn+:3]([CH3:5])[CH3:4]

참가 물질

4

반응물 2

HCID 125775-Nitro-2-Furoic AcidHCID 11217597Stannane, hydroxytrimethyl-

생성물 1

HCID 20429144HCID 20429144, 화합물수율 94%

시약·촉매·용매 1

HCID 241Benzene용매

반응 조건

온도
80 °C

실험 절차

Trimethyltin 5-nitro-2-furoate (Compound E) was prepared by reacting trimethyltin hydroxide (9.20 g, 0.0509 mole) with 5-nitro-2-furoic acid (8.00 g, 0.0509 mole) in 75 ml benzene. The reaction mixture was refluxed for 19 hours at a temperature of 80° C. and a pressure of 1 atm. The resulting precipitate was collected on filter paper and dried to yield 15.30 g (94%) of crude trimethyltin 5-nitro-2-furoate, melting point 188.2°-195.5° C. The resulting compound was recrystallized three times from benzene to give Compound E, melting point 190°-192° C. The elemental analysis gave (in %) C:30.15, H:3.74, N:4.43, Sn:36.89, calculated for C8H11NO5Sn (in %): C:30.04, H:3.47, N:4.38, Sn:37.12.

후처리

  1. customTrimethyltin 5-nitro-2-furoate (Compound E) was prepared
  2. customThe resulting precipitate was collected
  3. filtrationon filter paper
  4. customdried

출처 및 근거

ORD 기록
ord-93435abae8a64acb9c7cdfa3a0d8e20d
출처 데이터셋
uspto-grants-1985_02
특허 번호
US04497806

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