Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dibromoethane → 6-(2-Bromoethoxy)salicylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dibromoethane | HCID 7839 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,6-Dihydroxybenzamide | HCID 76602 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 6-(2-Bromoethoxy)salicylamide | HCID 13754423 | — |
반응 단계
A mixture of 23.0 g of 2,6-dihydroxybenzamide, 20.7 g of potassium carbonate and 28.2 g of 1,2-dibromoethane is refluxed, whilst stirring, for 2-3 hours in 300 ml of acetonitrile. The reaction mixture is filtered whilst still warm, the filtrate concentrated by evaporation and the residue recrystallised from a little methanol. 6-(2-Bromoethoxy)salicylamide having a melting point of 120°-121° is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04497813 |
| 출처 데이터셋 | uspto-grants-1985_02 |
| ORD ID | ord-47163b8fb6ae49a9b4394f743130485c |
| 출처 메모 | uspto-grants-1985_02 |