Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N,N-dipropyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Dipropylamine | HCID 8902 | — |
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 3-Isoquinolinecarboxylicacid, 1-(2-chlorophenyl)- | HCID 11000554 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N,N-dipropyl- | HCID 11057656 | 76.2% |
반응 단계
Operations are carried out as for Example 7, starting from 1.42 g of 1-(2-chlorophenyl) isoquinoline 3-carboxylic acid, 0.58 g of triethylamine, 0.62 g of ethyl chloroformate and 0.66 g of N-propyl propylamine in 50 ml of chloroform. 1.40 g of N,N-dipropyl 1-(2-chloro phenyl) isoquinoline 3-carboxamide, melting at 101° C., are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04499094 |
| 출처 데이터셋 | uspto-grants-1985_02 |
| ORD ID | ord-7dd1cd01cc0444419ddd184d7320cb67 |
| 출처 메모 | uspto-grants-1985_02 |