Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl acetamidocyanoacetate → Ethyl 2-cyano-2-acetamido-2-(2,3-dihydro-1H-inden-2yl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl acetamidocyanoacetate | HCID 95422 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 반응물 | 2-bromo-2,3-dihydro-1H-indene | HCID 10965463 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | Ethyl 2-cyano-2-acetamido-2-(2,3-dihydro-1H-inden-2yl)acetate | HCID 13517005 | — |
반응 단계
Sodium ethoxide (40 gms) was stirred in 1 L of dimethyl sulfoxide until solution was complete. Then, 100 g of ethyl acetamido-cyanoacetate was added, and again stirred until solution was complete. 2-Bromoindane (101 g) was slowly added, using a few ml of DMSO to wash the container and addition funnel. The solution was stirred over a weekend.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04500713 |
| 출처 데이터셋 | uspto-grants-1985_02 |
| ORD ID | ord-9fb38fe8ea064d439ab89cb9e2234f71 |
| 출처 메모 | uspto-grants-1985_02 |