Acetone → HCID 12962350, 화합물

HRID 616020노트

반응식

HRID 616020 반응식
[C:1]1([CH:7]2[NH:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(C)=O.C(N(CC)CC)C.[Cl:23][CH:24]([Cl:28])[C:25](Cl)=[O:26]>O>[C:1]1([CH:7]2[N:11]([C:25](=[O:26])[CH:24]([Cl:28])[Cl:23])[CH2:10][CH2:9][S:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

6

반응물 4

HCID 180AcetoneHCID 6593Dichloroacetyl chlorideHCID 8471TriethylamineHCID 207062-Phenylthiazolidine

생성물 1

HCID 12962350HCID 12962350, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Five grams of 2-phenyl thiazolidine was dissolved in 50 ml. of acetone, 3.1 g. of triethylamine was added and the mixture stirred in a room temperature water bath, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes and then poured into water, extracted with methylene chloride, separated, dried over magnesium sulfate, and the solvent stripped under vacuum. There was obtained a yield of 7.3 g. of an oil, the title compound, ND30 32 1.5836.

후처리

  1. extractionextracted with methylene chloride
  2. customseparated
  3. dry with materialdried over magnesium sulfate
  4. customThere was obtained a yield of 7.3 g

출처 및 근거

ORD 기록
ord-ce084045556940edb8db259006df819e
출처 데이터셋
uspto-grants-1978_02
특허 번호
US04072688

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