Methoxycarbonyl isothiocyanate → 1,2-Bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene

HRID 616111노트

반응식

HRID 616111 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:4][C:3]=1[NH2:13].[CH3:14][O:15][C:16]([N:18]=[C:19]=[S:20])=[O:17]>CC(C)=O>[CH3:14][O:15][C:16]([NH:18][C:19](=[S:20])[NH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:4][C:3]=1[NH:13][C:19]([NH:18][C:16]([O:15][CH3:14])=[O:17])=[S:20])=[O:17]

참가 물질

4

반응물 2

HCID 552246Methoxycarbonyl isothiocyanateHCID 203710591,2-Diamino-4-n-butylthiobenzene

생성물 1

HCID 203710011,2-Bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

1.5 G. of 1,2-diamino-4-n-butylthiobenzene in 30 ml. acetone is treated overnight with 4.5 g. methoxy carbonyl isothiocyanate at room temperature. The solution is concentrated, and the residue triturated with methanol and recrystallized from methanol, yielding 1,2-bis-(3-methoxycarbonyl-2-thioureido)-4-n-butylthiobenzene.

후처리

  1. customat room temperature
  2. concentrationThe solution is concentrated
  3. customthe residue triturated with methanol
  4. customrecrystallized from methanol

출처 및 근거

ORD 기록
ord-1fcb6efa55084cf587e8dcbb4d3dc644
출처 데이터셋
uspto-grants-1978_02
특허 번호
US04072696

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