Methoxycarbonyl isothiocyanate → 4-Carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene
반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9](=[O:11])[NH2:10])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][O:16][C:17]([N:19]=[C:20]=[S:21])=[O:18]>CC(C)=O>[C:9]([S:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:20]([NH:19][C:17]([O:16][CH3:15])=[O:18])=[S:21])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:11])[NH2:10]참가 물질
4
실험 절차
1 G. of 1-amino-4-carbamoylthio-2-nitrobenzene in 20 ml. acetone is treated with 3.0 g. methoxy carbonyl isothiocyanate at room temperature for several days. The solution is concentrated and the residue triturated with methanol to afford 4-carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene.
후처리
- concentrationThe solution is concentrated
- customthe residue triturated with methanol
출처 및 근거
- ORD 기록
- ord-04a64dede676417ab16f660662c95e2c
- 출처 데이터셋
- uspto-grants-1978_02
- 특허 번호
- US04072696
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