1-Bromo-2-Chloroethane → tert-butyl 5-(6-(2-chloroethoxy)-2-[(3-phenyl)phenyl)-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate

반응식

[C:1]1([C:7]2[CH:8]=[C:9]([C:13]3[N:22]=[C:21]([NH:23][C:24]4[CH:25]=[C:26]5[C:30](=[CH:31][CH:32]=4)[N:29]([C:33]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])=[O:34])[N:28]=[CH:27]5)[C:20]4[C:15](=[CH:16][C:17]([O:41][CH3:42])=[C:18]([OH:40])[CH:19]=4)[N:14]=3)[CH:10]=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:44][CH2:45][Cl:46].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[Cl:46][CH2:45][CH2:44][O:40][C:18]1[CH:19]=[C:20]2[C:15](=[CH:16][C:17]=1[O:41][CH3:42])[N:14]=[C:13]([C:9]1[CH:10]=[CH:11][CH:12]=[C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH:8]=1)[N:22]=[C:21]2[NH:23][C:24]1[CH:25]=[C:26]2[C:30](=[CH:31][CH:32]=1)[N:29]([C:33]([O:35][C:36]([CH3:37])([CH3:38])[CH3:39])=[O:34])[N:28]=[CH:27]2