Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl mercaptan → 5-Benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl mercaptan | HCID 7509 | — |
| 반응물 | Methyl heptanoate | HCID 7826 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 생성물 | 5-Benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester | HCID 54031523 | 78% |
반응 단계
In accordance with the process of Example 16, potassium t-butoxide (336 mg; 3 m mol), benzyl mercaptan (372 mg; 3 m mol) and 2-oxo-bicyclo 3.1.0! hexane-1-carboxylic acid methyl ester (463 mg; 3 m mol) were used in the reaction, and the reaction product was purified by a silica gel column chromatography with ethyl acetate and n-hexane (1.5; 8.5) to obtain 650 mg of 5-benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04073799 |
| 출처 데이터셋 | uspto-grants-1978_02 |
| ORD ID | ord-9ddf21f58ffd4e66a86d7463b454d7de |
| 출처 메모 | uspto-grants-1978_02 |