Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dimethylindole → 5-(2-ethyl-5-methyl-3-indolyl)-5-(1-benzyl-5-fluoro-3-indolyl)-3,4-dichloro-2(5H)-furanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dimethylindole | HCID 13408 | — |
| 반응물 | 1-Benzyl-5-fluoro-1H-indole | HCID 19796639 | — |
| 반응물 | 4-(2-Ethyl-5-methyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid | HCID 53738561 | — |
| 생성물 | 5-(2-ethyl-5-methyl-3-indolyl)-5-(1-benzyl-5-fluoro-3-indolyl)-3,4-dichloro-2(5H)-furanone | HCID 20442719 | — |
반응 단계
Following a procedure similar to that described above in part B of this example except that 4-(2-ethyl-5-methyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid is used in place of 4-(1,2-dimethyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid and 1-benzyl-5-fluoroindole is substituted for 1,2-dimethylindole, there is obtained 5-(2-ethyl-5-methyl-3-indolyl)-5-(1-benzyl-5-fluoro-3-indolyl)-3,4-dichloro-2(5H)-furanone (Formula V: R=R3 =H; R1 =CH3CH2 ; R2 =C6H5CH2 ; Y=5-CH3 ; Y1 =5-F).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04075224 |
| 출처 데이터셋 | uspto-grants-1978_02 |
| ORD ID | ord-a702d2d5f43045798fe6425e3caa9eaf |
| 출처 메모 | uspto-grants-1978_02 |