Benzaldehyde → 5-Benzylidene-2-thioxothiazolidin-4-one
반응식
[S:1]1[CH2:7][C:5](=[O:6])[NH:4][C:2]1=[S:3].[CH:8](=O)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.N1CCCCC1>C(O)C>[CH:8](=[C:7]1[S:1][C:2](=[S:3])[NH:4][C:5]1=[O:6])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1참가 물질
5
실험 절차
To a solution of 10 g (75.1 mmol) of rhodanine and 7.63 ml (75.1 mmol) of benzaldehyde in 150 ml of ethanol, 0.74 ml (7.5 mmol) of piperidine was added, and the mixture was heated under reflux for 5 hours. After cooling, the precipitated crystals were filtered and washed with cooled ethanol to give 11.07 g of the desired compound (66.6% yield, pale yellow crystals).
후처리
- temperaturethe mixture was heated
- temperatureunder reflux for 5 hours
- temperatureAfter cooling
- filtrationthe precipitated crystals were filtered
- washwashed with cooled ethanol
출처 및 근거
- ORD 기록
- ord-d824881d53434cb8beb91cc10043c497
- 출처 데이터셋
- uspto-grants-1993_09
- 특허 번호
- US05246948
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