Dichloromethane → HCID 19390523, 화합물
반응식
[CH2:1]([O:3][C:4]([NH:6][NH:7][CH:8]([CH3:10])[CH3:9])=[O:5])[CH3:2].C(=O)(O)[O-].[Na+].C(Cl)Cl.[N:19]#[C:20]Cl>O>[CH2:1]([O:3][C:4]([NH:6][N:7]([CH:8]([CH3:10])[CH3:9])[C:20]#[N:19])=[O:5])[CH3:2]참가 물질
6
실험 절차
73.0 g of 2-isopropylhydrazinecarboxylic acid ethyl ester and 42.0 g of sodium bicarbonate are stirred into 200 ml of methylene chloride and 400 ml of water. There is then introduced at room temperature in the course of 20 minutes, with continuous stirring, 30.8 g of gaseous cyanogen chloride. After an hour's stirring, the methylene chloride base is separated, dried over sodium sulphate and the solvent is distilled off in vacuo. There is obtained as residue 75.0 g (87.5% of theory) of 2-isopropyl-2-cyanohydrazinecarboxylic acid ethyl ester as colourless oil.
후처리
- customthe methylene chloride base is separated
- dry with materialdried over sodium sulphate
- distillationthe solvent is distilled off in vacuo
출처 및 근거
- ORD 기록
- ord-9b2990f0431544318ddbd48fceac40cf
- 출처 데이터셋
- uspto-grants-1978_02
- 특허 번호
- US04076938
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