Dimethylamine → HCID 178456694, 화합물
반응식
C(O[C:4]([NH:6][N:7]([CH:10]([CH3:12])[CH3:11])[C:8]#[N:9])=[O:5])C.[CH3:13][NH:14][CH3:15]>C(O)C>[CH:10]([N:7]1[C:8]([N:14]([CH3:15])[CH3:13])=[N:9][C:4]([OH:5])=[N:6]1)([CH3:12])[CH3:11]참가 물질
4
실험 절차
35.0 g of 2-isopropyl-2-cyanohydrazinecarboxylic acid ethyl ester is added dropwise to a solution of 100 ml of 33% dimethylamine in absolute ethanol. The solution is maintained firstly for 15 hours at room temperature and afterwards for 1 1/2 hours at reflux temperature (65° C). After concentration by evaporation to dryness there remains an oily residue, which slowly crystallises on standing. The semisolid product is washed with ethyl acetate. There is obtained 15.5 g (44% of theory) of 1-isopropyl-5-dimethylamino-3-hydroxy-1,2,4-triazole, m.p. 111°-112° C.
후처리
- temperatureat reflux temperature (65° C)
- concentrationAfter concentration
- customby evaporation to dryness
- customslowly crystallises
- washThe semisolid product is washed with ethyl acetate
출처 및 근거
- ORD 기록
- ord-c85c8adabeb546b6b1b417ef6b15dcaa
- 출처 데이터셋
- uspto-grants-1978_02
- 특허 번호
- US04076938
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