3-Nitrobenzylamine → 2,5-Dichloro-6-methyl 4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

반응식

[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH2:7][NH2:8])([O-:3])=[O:2].[Cl:12][C:13]1[N:14]=[C:15](Cl)[C:16]2[C:21]([Cl:22])=[C:20]([CH3:23])[S:19][C:17]=2[N:18]=1>>[Cl:12][C:13]1[N:14]=[C:15]([NH:8][CH2:7][C:6]2[CH:9]=[CH:10][CH:11]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[C:16]2[C:21]([Cl:22])=[C:20]([CH3:23])[S:19][C:17]=2[N:18]=1

참가 물질

반응물 2

HCID 1227223-Nitrobenzylamine

HCID 127242442,4,5-Trichloro-6-methyl-thieno-[2,3-d]-pyrimidine

생성물 1

HCID 184601062,5-Dichloro-6-methyl 4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

실험 절차

Following the procedure of Example 1, the reaction of 3-nitrobenzylamine with 2,4,5-trichloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2,5-dichloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

출처 및 근거

ORD 기록: ord-cd2afab4985b4b32ae1c64da7b0964e4
출처 데이터셋: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05948911

반응 노트

불러오는 중…